Season
- Season 21 2013-01-02
- Season 20 2012-01-03
- Season 19 2011-01-03
- Season 18 2010-03-01
- Season 17 2008-06-02
- Season 16 2007-09-17
- Season 15 2006-09-18
- Season 14 2005-06-06
- Season 13 2004-06-07
- Season 12 2003-06-02
- Season 11 2002-06-03
- Season 10 2002-04-30
- Season 9 2000-08-01
- Season 8 1999-07-30
- Season 7 1998-02-26
- Season 6 1997-12-05
- Season 5 1996-09-16
- Season 4 1996-03-07
- Season 3 1994-11-28
- Season 2 1993-06-25
- Season 1 1992-05-25
- Season 0 2014-02-06
Episode
- Episode 1: William Shatner; Chelsea Handler; Newton Faulkner
- Episode 2: Liv Tyler; Judd Apatow; Usher
- Episode 3: Jeff Foxworthy; Arianna Huffington; N.E.R.D.
- Episode 4: Dustin Hoffman; Gordon Ramsay; Flobots
- Episode 5: Will Smith; Pete Sampras; Ed Harcourt
- Episode 6: Russell Brand; Bill Engvall; Aimee Mann
- Episode 7: Justin Timberlake; Karen Allen; Sheryl Crow
- Episode 8: Dana Carvey; Spencer Breslin; Priscilla Ahn
- Episode 9: Mike Myers; Abigail Breslin; David Cook
- Episode 10: Larry the Cable Guy; Bob Costas; Ashanti
- Episode 11: Anne Hathaway; Gabriel Iglesias; Amos Lee
- Episode 12: Don Rickles; Charles Barkley, Kenny Smith, Ernie Johnson; Jewel
- Episode 13: The Rock; Tom Papa; Against Me!
- Episode 14: Wanda Sykes; James McAvoy; Duffy
- Episode 15: Bette Midler; Al Roker; Bette Midler
- Episode 16: Selma Blair; Kevin Nealon; Steve Tyrell
- Episode 17: Aaron Eckhart; Los Lonely Boys; Dara Torres
- Episode 18: Sara Bareilles; Jarod Miller
- Episode 19: Adam Carolla; Kathy Griffin; Wynton Marsalis; Willie Nelson
- Episode 20: Elizabeth Banks; Michael Caine
- Episode 21: Will Ferrell; Mary McCormack; James Hunter
- Episode 22: David Duchovny; Reese Hoffa; Jakob Dylan
- Episode 23: John C. Reilly; Venus Williams; Gavin Rossdale
- Episode 24: David Spade; Jordana Spiro; Coldplay
- Episode 25: Tim Allen; Demi Lovato; One Republic
- Episode 26: Kyra Sedgewick; Chris Matthews; Alanis Morissette
- Episode 27: Gillian Anderson; Dave Attell; The Duke Spirit
- Episode 28: Kevin Costner; D.L. Hughley; The Time
- Episode 29: Kelsey Grammer; Hugh Rowland; Drew Sherwood; Gavin Degraw
- Episode 30: Kevin Spacey; Triumph the Insult Comic Dog; Jesse McCarthy
- Episode 31: Julie Scardina; Brendan Fraser; Gnarls Barkley
- Episode 32: Seth Rogen; Joan Allen; Third Day
- Episode 33: Rainn Wilson; Emeril Lagasse; Sergio Mendes Ft. Ledisi
- Episode 34: Rosie Perez; Robin Thicke
- Episode 35: Bill Cosby; Emma Stone
- Episode 36: Ben Stiller; the Jonas Brothers
- Episode 37: Robert Downey Jr.; Anna Faris; Toby Keith
- Episode 38: Jack Black; Conor Oberst
- Episode 39: Nick Nolte; Solomon Burke
- Episode 40: Scarlett Johansson; Luke Ford; Chris Cornell
- Episode 41: John McCain; Dara Torres; Juliana Hatfield
- Episode 42: Norm MacDonald; Gordon Ramsay; B.B. King
- Episode 43: Bill Maher; Low vs Diamond
- Episode 46: Josh Brolin, Chelsea Handler, The Killers
- Episode 47: Heidi Klum, Robert Pattinson, Seal
- Episode 48: Debra Messing, Cody Willard, Celine Dion
- Episode 49: Kathy Griffin, David Frost, Colbie Caillat
- Episode 50: Michael Phelps, JB Smoove
- Episode 51: Brian Williams, Kirk Fox, Common
- Episode 52: Cate Blanchett, Tim Reid & Tom Dreesen, Taylor Swift
- Episode 53: Will Smith, Paula Deen, k.d. lang
- Episode 55: Kate Beckinsale, Sean "Diddy" Combs, Sara Bareilles & Ingrid Michaelson
- Episode 56: Wanda Sykes, Michael Phelps, Lyle Lovett
- Episode 57: Jamie Foxx, David Gregory
- Episode 58: Kate Winslet, Dame Edna, Sheryl Crow
- Episode 59: Jim Carrey, Rosario Dawson, Relient K
- Episode 60: Charlize Theron; Matt Lucas & David Walliams
- Episode 61: Adam Sandler, Zooey Deschanel, Los Lonely Boys
- Episode 62: James Franco, Doris Kearns Goodwin, Melissa Etheridge
- Episode 64: Owen Wilson, Julie Scardina, Natalie Cole
- Episode 65: Terry Bradshaw, Jack Witherspoon, Iron & Wine
- Episode 66: Queen Latifah, Adam Carolla, Pussycat Dolls
- Episode 67: Anne Hathaway, Brady Barr, Jeff Dunham
- Episode 68: Dustin Hoffman, Mary Lynn Rajskub, Lady GaGa
- Episode 69: Daniel Craig, Taraji P. Henson, Eagles of Death Metal
- Episode 70: David Duchovny, Richard Roeper, The All-American Rejects
- Episode 71: Mickey Rourke, Toni Collette, John Legend
- Episode 72: Cherie Blair, Ralph Fiennes, Brett Dennen
- Episode 73: Kevin James, Emma Roberts, MuteMath
- Episode 74: Hugh Laurie, Chuck Todd, Band From TV
- Episode 75: Jimmy Fallon, Neil DeGrasse Tyson, Lee Ann Womack
- Episode 76: Wanda Sykes, Bernice Gallego, Buckcherry
- Episode 77: Howie Mandel, Jerome Bettis, Lady Antebellum
- Episode 79: Marisa Tomei, Dr. Grey Stafford, Ty Barnett
- Episode 80: Michelle Obama; Chris Rock; Darius Rucker
- Episode 81: Rainn Wilson, Nikki Glaser, Hoobastank
- Episode 82: Dakota Fanning, Bradley Cooper, the Neville Brothers
- Episode 83: Jenna Fischer, Justin Long, Franz Ferdinand
- Episode 84: Elizabeth Banks, Dev Patel, James Morrison
- Episode 85: Kate Winslet, Danny Boyle, Akon
- Episode 86: Penelope Cruz, D.L. Hughley, Sara Bareilles
- Episode 87: Drew Barrymore, Serena Williams, will.i.am
- Episode 88: Jennifer Aniston, Santonio Holmes, Jamey Johnson
- Episode 89: Dave Salmoni, Frank Langella, Ben Lee
- Episode 90: Simon Baker, Heidi Montag and Spencer Pratt, Duffy
- Episode 91: Bill Maher, Viola Davis, Raphael Saadiz
- Episode 92: Anderson Cooper; Steve Byrne; Sarah McLachlan
- Episode 93: Miley Cyrus; Jason Statham; David Cook
- Episode 94: Kiefer Sutherland; Lisa Lampanelli; Barry Manilow
- Episode 95: Larry the Cable Guy, Chris Matthews, Adele
- Episode 96: Bill Maher, Kristin Chenoweth, Nickelback
- Episode 97: Hugh Jackman, Tenacious D
- Episode 98: Jay Mohr, Marjorie Johnson, Scott Weiland
- Episode 99: Ron Howard, Jonas Brothers
- Episode 100: Larry the Cable Guy, Malin Akerman, the Fray
- Episode 101: Bob Newhart, Rachel Maddow, Bettye Lavette
- Episode 102: Russell Brand, Neko Case
- Episode 103: Jarrod Miller, Sienna Miller, Tom Jones
- Episode 104: Christina Ricci, Papa Roach
- Episode 105: Elisabeth Hasselbeck, Demetri Martin, Rocco De Luca & The Burden
- Episode 106: Whoopi Goldberg, Elle Fanning, Keyshia Cole
- Episode 107: Ellen DeGeneres, Christopher Mintz, Raul Malo
- Episode 108: Dwayne Johnson, Heather Headley
- Episode 109: John Krasinski, Kara DioGuardi, Randy Travis
- Episode 110: Tom Cruise, Frank Caliendo, The Cure
- Episode 111: Portia de Rossi, D.L. Hughley, Soundtrack of Our Lives
- Episode 112: Reese Witherspoon, Keith Olbermann, Naturally 7
- Episode 113: President Barack Obama, Garth Brooks
- Episode 117: Robin Williams, Freida Pinto, Johnny Mathis
- Episode 151: Charlie Sheen, Arianna Huffington, Lisa Hannigan
- Episode 168: Seth Rogen, Guy Fieri, Chris Cornell
- Episode 169: Simon Cowell, Randy Jackson, Ryan Seacrest, John Cena, Playing For Change
- Episode 170: Condoleezza Rice, Bill Hader, PJ Harvey & John Parish
- Episode 171: Halle Berry, Frank Caliendo, Prince
- Episode 172: Paul Giamatti, Emma Roberts, Prince
- Episode 173: Dana Carvey, Billy Mays, Prince
- Episode 174: Vin Diesel, Lisa Lampanelli, Gavin DeGraw
- Episode 175: Amy Poehler, Paul Walker, Fall Out Boy
- Episode 176: Michael Caine, Dennis Rodman, Christopher Guest, Michael McKean, Harry Shearer
- Episode 177: Ben Affleck, Taylor Swift
- Episode 178: Miley Cyrus, Tom Lennon
- Episode 179: Sen. John McCain, Kristin Chenoweth, Billy Ray Cyrus
- Episode 180: Jamie Foxx, Carol Leifer, the Airborne Toxic Event
- Episode 181: Don Rickles, Richard Engel, Chris Botti featuring John Mayer
- Episode 182: Jessica Alba, Bob Saget, Jonny Lang
- Episode 183: Charles Barkley, Leslie Mann, TV on the Radio
- Episode 184: Martha Stewart, Tracey Ullman, the Killers
- Episode 185: Hugh Jackman, Abigail Breslin, Ida Maria
- Episode 186: Robert Downey Jr., Alexandra Wentworth, George Wallace
- Episode 187: Eric Bana, Marjorie Johnson, Big Bad Voodoo Daddy
- Episode 188: Michael Douglas, Chelsea Handler, Country Bones
- Episode 189: Jimmy Fallon, Chris Matthews, Zac Brown Band
- Episode 190: Matthew McConaughey, Earvin "Magic" Johnson, Starsailor
- Episode 191: Arsenio Hall, Jules Sylvester, Ziggy Marley
- Episode 192: Anderson Cooper, Kathleen Madigan, Eli Young Band
- Episode 193: Howie Mandel, Alec Greven, Robert Randolph & the Clark Sisters
- Episode 194: Tim Allen, John Cho, Van Morrison
- Episode 195: Adam Sandler, Judd Apatow, Soulja Boy Tellem
- Episode 196: Jamie Lee Curtis, Jonah Hill, Jewel
- Episode 197: Russell Brand, Elizabeth Banks, Ciara
- Episode 198: Dennis Miller, Calvin Borel, Kelly Clarkson
- Episode 199: Kevin Spacey, Roberta McCain, Yusuf
- Episode 200: Katie Couric, Ewan McGregor, the Decemberists
- Episode 201: Kevin Bacon, Julie Scardina, Kings of Leon
- Episode 202: Cameron Diaz, Kirk Fox, Blink 182
- Episode 203: Terry Bradshaw, 8-year-old piano prodigy Ethan Bortnick, Blink 182
- Episode 204: Bill Maher, Adam Richman, Mandy Moore
- Episode 205: Andy Samberg, "American Idol" winner Kris Allen, Lionel Richie
- Episode 206: Brian Williams, Jesse James, Tori Amos
- Episode 207: Mel Gibson, Lyle Lovett
- Episode 208: Gov. Arnold Schwarzenegger, Dwight Yoakam
- Episode 209: Wanda Sykes, Sarah McLachlan
- Episode 210: Billy Crystal, Prince
- Episode 211: Conan O'Brien, James Taylor
- Episode 212: 17 Dec. 2008
The Tonight Show with Jay Leno Season 17 Jamie Foxx, Carol Leifer, the Airborne Toxic Event
Jay Leno hosts some of the biggest celebrities in the world.
